Ac-DNLD-AMC

Description: Ac-DNLD-AMC is a fluorogenic caspase-3 substrate. Upon enzymatic cleavage by caspase-3, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-3 activity. AMC displays excitation/emission maxima of 340-360 and 440-460 nm, respectively. Smiles: CC=1C=2C(=CC(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)NC(C)=O)=O)CC(N)=O)=O)CC(C)C)=O)CC(O)=O)=O)=CC2)OC(=O)C1