Abrocitinib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1... more
Product information "Abrocitinib"
Description: Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2). Target: JAK. Smiles: CCCS(=O)(=O)N[C@H]1C[C@H](C1)N(C)c1ncnc2[nH]ccc12. References: Vazquez ML, et al. Identification of N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases. J Med Chem. 2018 Feb 8,61(3):1130-1152.
| Keywords: | PF-04965842 |
| Supplier: | TargetMol |
| Supplier-Nr: | TQ0037 |
Properties
| Application: | Targets Janus kinase 1 [EC:2.7.10.2] (JAK1) |
| MW: | 323.41 D |
| Formula: | C14H21N5O2S |
Database Information
| CAS : | 1622902-68-4| Matching products |
| KEGG ID : | K11217 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H361 |
| P Phrases: | P201, P202, P280, P308+313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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