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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| Cay27853-1 | 1 mg | - | - |
6 - 10 business days* |
810.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase... more
Product information "8-hydroxy Efavirenz"
8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz (Cay-14412). 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B6. It induces apoptosis in rat primary hippocampal neurons and loss of dendritic spines in rat primary hippocampal neuronal cultures when used at a concentration of 0.01 µM.Formal Name: (4S)-6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. CAS Number: 205754-33-2. Molecular Formula: C14H9ClF3NO3. Formula Weight: 331.7. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: soluble, DMSO: soluble, Methanol: soluble. SMILES: ClC1=CC(O)=C2C([C@@](C#CC3CC3)(C(F)(F)F)OC(N2)=O)=C1. InChi Code: InChI=1S/C14H9ClF3NO3/c15-8-5-9-11(10(20)6-8)19-12(21)22-13(9,14(16,17)18)4-3-7-1-2-7/h5-7,20H,1-2H2,(H,19,21). InChi Key: OOVOMPCQLMFEDT-UHFFFAOYSA-N.
| Keywords: | (4S)-6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 27853 |
Properties
| Application: | Oxidative metabolite |
| MW: | 331.7 D |
| Formula: | C14H9ClF3NO3 |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 205754-33-2| Matching products |
| KEGG ID : | K17709 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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