7beta-hydroxy Cholesterol

7beta-hydroxy Cholesterol is an oxysterol formed by enzymatic and non-enzymatic oxidation of cholesterol. It is the primary oxysterol found in LDL and induces apoptosis and cell death of human umbilical vein endothelial cells (HUVECs) in vitro in a concentration-dependent manner. Increased plasma levels of 7beta-hydroxy cholesterol positively correlate with mortality in coronary heart disease in human males.Formal Name: (3beta,7beta)-cholest-5-ene-3,7-diol. CAS Number: 566-27-8. Synonyms: 7beta-Hydroxycholesterol, 7beta-OHC. Molecular Formula: C27H46O2. Formula Weight: 402.7. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 2 mg/ml, DMSO: 0.1 mg/ml, Ethanol: 20 mg/ml, Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml. lambdamax: 237 nm. SMILES: O[C@H](C1)CC[C@@]2(C)C1=C[C@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCCC(C)C. InChi Code: InChI=1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-25,28-29H,6-15H2,1-5H3/t18-,20+,21-,22+,23+,24+,25+,26+,27-/m1/s1. InChi Key: OYXZMSRRJOYLLO-KGZHIOMZSA-N.