7-Methylguanine

7-Methylguanine is a metabolite of the natural purine base whose N9 position is available for chemical modifications. This genotoxic adduct can be generated by DNA methylation and has been used as a probe of protein-DNA interactions and for DNA sequencing methods. It is also considered to be a carcinogenic biomarker for cigarette smoking that is detectable in urine.Formal Name: 2-amino-1,7-dihydro-7-methyl-6H-purin-6-one. CAS Number: 578-76-7. Synonyms: Epiguanine, 2-Amino-7-methylhypoxanthine, N7-Methylguanine, NSC 193444, NSC 19647. Molecular Formula: C6H7N5O. Formula Weight: 165.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: 1 M NaOH: 50 mg/ml. lambdamax: 252, 281 nm. SMILES: O=C1C2=C(N=CN2C)NC(N)=N1. InChi Code: InChI=1S/C6H7N5O/c1-11-2-8-4-3(11)5(12)10-6(7)9-4/h2H,1H3,(H3,7,9,10,12). InChi Key: FZWGECJQACGGTI-UHFFFAOYSA-N.