6-(4-Methoxyphenyl)-3-pyridazinamine

Ionotropic GABAA receptors are ligand-gated ion channels that facilitate the passing of chloride ions across the cell membrane and promote an inhibitory influence on target neurons. These receptors are the major targets for benzodiazepines and related anxiolytic drugs. 6-(4-Methoxyphenyl)-3-pyridazinamine is an aminopyridazine derivative that acts as a GABAA receptor antagonist. It can also be used as an intermediate in the synthesis of SR 95531 (Cay-14585).Formal Name: 6-(4-methoxyphenyl)-3-pyridazinamine. CAS Number: 4776-87-8. Molecular Formula: C11H11N3O. Formula Weight: 201.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 15 mg/ml, DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml, Ethanol: 10 mg/ml. lambdamax: 274 nm. SMILES: NC1=NN=C(C2=CC=C(OC)C=C2)C=C1. InChi Code: InChI=1S/C11H11N3O/c1-15-9-4-2-8(3-5-9)10-6-7-11(12)14-13-10/h2-7H,1H3,(H2,12,14). InChi Key: PCPMUYYPWJFHEQ-UHFFFAOYSA-N.