5-fluoro 203
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: 5-fluoro 203 (NSC-703786) is a cytotoxic molecule leading to cell death by forming... more
Product information "5-fluoro 203"
Description: 5-fluoro 203 (NSC-703786) is a cytotoxic molecule leading to cell death by forming DNA adducts. 5-fluoro 203 induces aryl hydrocarbon receptor signaling, and elevates expression of CYP1A1. 5-fluoro 203 treatment of cells also leads to elevation of reactive oxygen species and activation of p38, JNK and ERK. Target: Others. Smiles: Cc1cc(ccc1N)-c1nc2cc(F)ccc2s1. References: Mclean L S , Watkins C N , Campbell P , et al. Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells[J]. Chemical Research in Toxicology, 2015, 28(5):855-71.
| Keywords: | 5F-203, NSC-703786 |
| Supplier: | TargetMol |
| Supplier-Nr: | T21704 |
Properties
| Application: | Aryl hydrocarbon receptor activator |
| MW: | 258.31 D |
| Formula: | C14H11FN2S |
Database Information
| CAS : | 260443-89-8| Matching products |
| KEGG ID : | K09093 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
|
| H Phrases: | H302 |
| P Phrases: | P264, P270, P301+310, P330, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
Viewed