5-Azacytidine

Description: 5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity. 5-Azacytidine regulates gene expression by decreasing the level of DNA methylation. 5-Azacytidine induces autophagy and has antitumor activity. Target: Nucleoside Antimetabolite/Analog, Antibacterial, Antibiotic, Autophagy, DNA Methyltransferase. Smiles: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(N)N=C2. References: Gailhouste L, et al. Epigenetic reprogramming using 5-azacytidine promotes an anti-cancer response in pancreatic adenocarcinoma cells. Cell Death Dis. 2018 May 1,9(5):468.