4-Methylamino antipyrine hydrochloride

Description: 4-Methylamino antipyrine hydrochloride, an active metabolite of Metamizole, a pyrazolone non-steroidal anti-inflammatory drug (NSAID) that inhibits COX, possesses analgesic, antipyretic, and relatively weak anti-inflammatory properties. Target: COX. Smiles: Cl.O=C1C(NC)=C(N(N1C=2C=CC=CC2)C)C. References: Burmanczuk A, et al. Pharmacokinetic investigations of the marker active metabolites 4-methylamino-antipyrine and 4-amino-antipyrine after intramuscular injection of metamizole in healthy piglets. J Vet Pharmacol Ther. 2016 Dec,39(6):616-620.