4-Hydroxyhippuric Acid

4-Hydroxyhippuric Acid is a dihydroxy phenolic acid inhibitor of organic anion transporter 1 (OAT1, IC50 = 25 µM in opossum kidney cells). It increases the production of free radicals in opossum kidney cells expressing human OAT1. 4-Hydroxyhippuric Acid reduces the secretion of TNF-alpha, but not IL-1beta or IL-6, in isolated human peripheral blood mononuclear cells (PBMCs) stimulated with LPS by 30.4% when used at a concentration of 1 µM.Formal Name: N-(4-hydroxybenzoyl)-glycine. CAS Number: 2482-25-9. Synonyms: p-Hydroxyhippuric Acid, para-Hydroxyhippuric Acid. Molecular Formula: C9H9NO4. Formula Weight: 195.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 1 mg/ml, DMF:PBS (pH 7.2) (1:10): 0.09 mg/ml. lambdamax: 254 nm. SMILES: OC1=CC=C(C(NCC(O)=O)=O)C=C1. InChi Code: InChI=1S/C9H9NO4/c11-7-3-1-6(2-4-7)9(14)10-5-8(12)13/h1-4,11H,5H2,(H,10,14)(H,12,13). InChi Key: ZMHLUFWWWPBTIU-UHFFFAOYSA-N.