4-Epidoxycycline

4-Epidoxycycline
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay23225-500 500 µg -

6 - 10 business days*

617.00€
Cay23225-1 1 mg -

6 - 10 business days*

923.00€
 
4-Epidoxycycline is the 4-epimer hepatic metabolite of the antibiotic doxycycline (Cay-14422).... more
Product information "4-Epidoxycycline"
4-Epidoxycycline is the 4-epimer hepatic metabolite of the antibiotic doxycycline (Cay-14422). Unlike doxycycline, 4-epidoxycycline lacks antibiotic activity, therefore, it may not induce the intestinal inflammation in mice associated with doxycycline use. It is an alternative to doxycycline to inactivate the transactivator protein tTA or activate the reverse transactivator rtTA protein in Tet-Off- and Tet-On-based gene expression systems in vitro and in mice.Formal Name: (4R,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide. CAS Number: 6543-77-7. Synonyms: 4-ED. Molecular Formula: C22H24N2O8. Formula Weight: 444.4. Purity: >70%. Formulation: (Request formulation change), A solid. Solubility: DMSO: slightly soluble, Methanol: slightly soluble. SMILES: OC1=C2C([C@H](C)[C@]3([H])C(C2=O)=C(O)[C@@]4(O)[C@@]([C@@H](N(C)C)C(O)=C(C(N)=O)C4=O)([H])[C@H]3O)=CC=C1. InChi Code: InChI=1S/C22H24N2O8/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31)/t7-,10+,14+,15+,17-,22-/m0/s1. InChi Key: JBIWCJUYHHGXTC-NLJUDYQYSA-N.
Keywords: 4-ED, (4R,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
Supplier: Cayman Chemical
Supplier-Nr: 23225

Properties

Application: Doxycycline metabolite, Tet-Off- and Tet-On-based gene expression system
MW: 444.4 D
Formula: C22H24N2O8
Purity: >70%
Format: Solid

Database Information

CAS : 6543-77-7| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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