(3S,5S)-Atorvastatin (sodium salt)

(3S,5S)-Atorvastatin (sodium salt)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay18465-1 1 mg -

6 - 10 business days*

100.00€
Cay18465-5 5 mg -

6 - 10 business days*

442.00€
Cay18465-10 10 mg -

6 - 10 business days*

781.00€
 
Atorvastatin (Cay-10493) is an HMG-CoA reductase inhibitor (IC50 = 154 nM) that is effective... more
Product information "(3S,5S)-Atorvastatin (sodium salt)"
Atorvastatin (Cay-10493) is an HMG-CoA reductase inhibitor (IC50 = 154 nM) that is effective against hypercholesterolemia and certain dyslipidemias. Atorvastatin can exist in four optical forms, with the 3R,5R enantiomer displaying the greatest activity against HMG-CoA reductase. (3S,5S)-Atorvastatin is an enantiomer of atorvastatin that has little or no inhibitory activity against HMG-CoA reductase. It also differs from other atorvastatin enantiomers in cytotoxicity, activation of the pregnane X receptor, and induction of cytochrome P450 isoforms.Formal Name: 2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid, monosodium salt. CAS Number: 1428118-38-0. Molecular Formula: C33H34FN2O5 . Na. Formula Weight: 580.6. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/mL, DMF:PBS (pH 7.2) (1:9): 0.1 mg/mL, DMSO: 15 mg/mL, Ethanol: 0.5 mg/mL. lambdamax: 246 nm. SMILES: O=C(C1=C(C(C)C)N(CC[C@H](O)C[C@H](O)CC([O-])=O)C(C2=CC=C(F)C=C2)=C1C3=CC=CC=C3)NC4=CC=CC=C4.[Na+]. InChi Code: InChI=1S/C33H35FN2O5.Na/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40,/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40),/q,+1/p-1/t26-,27-,/m0./s1. InChi Key: VVRPOCPLIUDBSA-WMXJXTQLSA-M.
Keywords: 2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid, monosodium salt
Supplier: Cayman Chemical
Supplier-Nr: 18465

Properties

Application: Inactive enantiomer
MW: 580.6 D
Formula: C33H34FN2O5 . Na
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 1428118-38-0| Matching products
KEGG ID : K00021 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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