3CAI
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: 3CAI is a potent and specific AKT1 and AKT2 inhibitor, demonstrating significant... more
Product information "3CAI"
Description: 3CAI is a potent and specific AKT1 and AKT2 inhibitor, demonstrating significant inhibition of AKT in an in vitro kinase assay. It suppressed the expression of AKT direct downstream targets (such as mTOR and GSK3beta) and induced growth inhibition and apoptosis in colon cancer cells. Target: Akt. Smiles: ClCC(=O)c1c[nH]c2ccccc12. References: Kim DJ, et al. (3-Chloroacetyl)-indole, a novel allosteric AKT inhibitor, suppresses colon cancer growth in vitro and in vivo. Cancer Prev Res (Phila). 2011 Nov,4(11):1842-51.
| Supplier: | TargetMol |
| Supplier-Nr: | T14034 |
Properties
| Application: | Akt1 / Akt2 inhibitor |
| MW: | 193.63 D |
| Formula: | C10H8ClNO |
Database Information
| CAS : | 28755-03-5| Matching products |
| KEGG ID : | K04456 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H319 |
| P Phrases: | P264, P270, P280, P330, P301+P310, P305+P351+P338, P337+P313, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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