3,6-dichloro-benzo[b]thiophene-2-Carboxylic Acid

3,6-dichloro-benzo[b]thiophene-2-Carboxylic acid is an inhibitor of myeloid cell leukemia 1 (Mcl-1) with a Ki value of 59 µM for binding of FITC-Mcl-1-BH2 peptide binding to Mcl-1. It has been used as a building block in the synthesis of inhibitors of Mcl-1, the toll-like receptor 3/double-stranded RNA (TLR3/dsRNA) complex, and D-amino acid oxidase (DAO).Formal Name: 3,6-dichloro-benzo[b]thiophene-2-carboxylic acid. CAS Number: 34576-94-8. Molecular Formula: C9H4Cl2O2S. Formula Weight: 247.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 1 mg/ml. lambdamax: 239, 251, 296 nm. SMILES: ClC1=CC=C(C(Cl)=C(C(O)=O)S2)C2=C1. InChi Code: InChI=1S/C9H4Cl2O2S/c10-4-1-2-5-6(3-4)14-8(7(5)11)9(12)13/h1-3H,(H,12,13). InChi Key: AAHPIJMQJAZYTM-UHFFFAOYSA-N.