20-Deoxyingenol

20-Deoxyingenol is a diterpenoid that has been found in E. kansui and has antioxidant and osteoprotective activities. It inhibits oxidative stress-induced decreases in autophagic flux and apoptosis in isolated mouse chondrocytes when used at a concentration of 10 mM. 20-Deoxyingenol (20 mg/kg per day, i.p.) reduces bone erosion and cartilage calcification in joints in a mouse model of injury-induced osteoarthritis.Formal Name: 1aR,2S,5R,5aS,6S,9,10,10aR-octahydro-5,5a,6-trihydroxy-1,1,4,7,9R-pentamethyl-1H-2,8aS-methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one. CAS Number: 54706-99-9. Molecular Formula: C20H28O4. Formula Weight: 332.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 1 mg/ml, DMSO: 1 mg/ml. SMILES: O[C@@H](C(C)=C[C@]12[C@@H](C[C@@]34[H])C)[C@@]2(O)[C@@H](C(C)=C[C@@H](C1=O)[C@@]4(C3(C)C)[H])O. InChi Code: InChI=1S/C20H28O4/c1-9-6-12-14-13(18(14,4)5)7-11(3)19(17(12)23)8-10(2)16(22)20(19,24)15(9)21/h6,8,11-16,21-22,24H,7H2,1-5H3/t11-,12-,13-,14+,15-,16+,19+,20+/m1/s1. InChi Key: FOSYZKSOJUQLTD-VCQBTUPJSA-N. Origin: Plant/Herba Epimedii.