2-Thenoyltrifluoroacetone

2-Thenoyltrifluoroacetone (TTFA) is an inhibitor of respiration in animals and bacteria. In animals, TTFA binds at the quinone reduction site of succinate:ubiquinone oxidoreductase (SQR, Complex II), preventing ubiquinone from binding. It inhibits NADH fumarate reductase in bacteria. TTFA also inhibits photosystem II in plants and NADH-ubiquinone oxidoreductase of the virus Vibrio cholerae, decreasing cholera toxin production. This compound is also a chelator of metals, including lanthanum, zirconium, hafnium, and neodymium.Formal Name: 4,4,4-trifluoro-1-(2-thienyl)-1,3-butanedione. CAS Number: 326-91-0. Synonyms: NSC 66544, NSC 405702, NSC 405703, NSC 405704, NSC 405705, NSC 405706, TTFA. Molecular Formula: C8H5F3O2S. Formula Weight: 222.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml. lambdamax: 324, 326, 355 nm. SMILES: O=C(C1=CC=CS1)CC(C(F)(F)F)=O. InChi Code: InChI=1S/C8H5F3O2S/c9-8(10,11)7(13)4-5(12)6-2-1-3-14-6/h1-3H,4H2. InChi Key: TXBBUSUXYMIVOS-UHFFFAOYSA-N.