2-p-Toluidinylnaphthylene-6-sulfonate (sodium salt)

2-p-Toluidinylnaphthylene-6-sulfonate (TNS) is a fluorescent probe for the conformational state of proteins. Upon binding to the hydrophobic surface of proteins, TNS displays excitation and emission maxima of 321 and 446 nm, respectively. It has also been used to determine the pKa values of lipid nanoparticles (LNPs).Formal Name: 6-[(4-methylphenyl)amino]-2-naphthalenesulfonic acid, monosodium salt. CAS Number: 53313-85-2. Synonyms: 6-(p-Toluidino)-2-naphthalenesulfonic Acid, TNS. Molecular Formula: C17H14NO3S . Na. Formula Weight: 335.4. Purity: >98%. Emission: 446 nm. Excitation: 321 nm. Formulation: (Request formulation change), A solid. Solubility: Ethanol: Slightly soluble. lambdamax: 225, 274, 318 nm. SMILES: O=S([O-])(C1=CC=C2C=C(NC3=CC=C(C)C=C3)C=CC2=C1)=O.[Na+]. InChi Code: InChI=1S/C17H15NO3S.Na/c1-12-2-6-15(7-3-12)18-16-8-4-14-11-17(22(19,20)21)9-5-13(14)10-16,/h2-11,18H,1H3,(H,19,20,21),/q,+1/p-1. InChi Key: QZZGQOXRGFDEJP-UHFFFAOYSA-M.