2-oxo Clopidogrel

Description: 2-oxo Clopidogrel is an intermediary metabolite of clopidogrel . Clopidogrel is a prodrug that is converted to its active metabolite via two sequential oxidative steps. The first step leads to formation of 2-oxo clopidogrel, followed by conversion to the active metabolite, which binds specifically and irreversibly to the platelet P2Y12 purinergic receptor, inhibiting ADP-mediated platelet activation and aggregation. Target: Others. Smiles: COC(=O)C(N1CCC2SC(=O)C=C2C1)C1=CC=CC=C1Cl