2,5-dimethyl Celecoxib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: 2,5-dimethyl Celecoxib is a celecoxib derivative and a targeted inhibitor of... more
Product information "2,5-dimethyl Celecoxib"
Description: 2,5-dimethyl Celecoxib is a celecoxib derivative and a targeted inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1), a key enzyme in the PGE2 synthesis pathway of inflammatory mediators. Target: Prostaglandin Receptor, Apoptosis, Wnt/beta-catenin. Smiles: CC1=CC(C2=CC(=NN2C2=CC=C(C=C2)S(N)(=O)=O)C(F)(F)F)=C(C)C=C1. References: Majchrzak-Celinska A, et al. COXIBs and 2,5-dimethylcelecoxib counteract the hyperactivated Wnt/beta-catenin pathway and COX-2/PGE2/EP4 signaling in glioblastoma cells. BMC Cancer. 2021 May 3,21(1):493.
| Supplier: | TargetMol |
| Supplier-Nr: | T35610 |
Properties
| Application: | mPGES-1 inhibitor |
| MW: | 395.4 D |
| Formula: | C18H16F3N3O2S |
Database Information
| CAS : | 457639-26-8| Matching products |
| KEGG ID : | K15729 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301 |
| P Phrases: | P264, P270, P301+310, P321, P330, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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