10-Formyltetrahydrofolate (sodium salt) (technical grade)

10-Formyltetrahydrofolate is a formyl donor and cofactor, as well as a metabolite of 5,10-methylenetetrahydrofolic acid (folitixorin, Cay-33967). It is formed from 5,10-methylenetetrahydrofolic acid by methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) in the cytosol and MTHFD2 and MTHFD2L in the mitochondria. 10-Formyltetrahydrofolate provides the formyl group for conjugation to methionine-tRNA, which is required for mitochondrial protein translation initiation, and is also involved in purine biosynthesis.Formal Name: N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-L-glutamic acid, disodium salt. CAS Number: 914800-65-0. Synonyms: 10-CHO-FH4, 10-CHO-THF, N10-Formyltetrahydrofolate, 10-formyl H4PteGlu, 10-fTHF. Molecular Formula: C20H21N7O7 . 2Na. Formula Weight: 517.4. Formulation: (Request formulation change), A solid. Solubility: Methanol: slightly soluble, Water: slightly soluble. SMILES: O=C1C2=C(NC(N)=N1)NCC(N2)CN(C3=CC=C(C=C3)C(N[C@H](C([O-])=O)CCC([O-])=O)=O)C=O.[Na+].[Na+]. InChi Code: InChI=1S/C20H23N7O7.2Na/c21-20-25-16-15(18(32)26-20)23-11(7-22-16)8-27(9-28)12-3-1-10(2-4-12)17(31)24-13(19(33)34)5-6-14(29)30,,/h1-4,9,11,13,23H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,22,25,26,32),,/q,2*+1/p-2/t11?,13-,,/m0../s1. InChi Key: YAAHOQFUMOTHOP-UAAMANLASA-L.