1,5-Isoquinolinediol
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: 1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1, IC50:... more
Product information "1,5-Isoquinolinediol"
Description: 1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1, IC50: 0.39 µM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. This compound can be used with cells in culture and in animals. Target: PARP. Smiles: Oc1cccc2c(O)nccc12. References: Davar D, et al. Role of PARP inhibitors in cancer biology and therapy.[J]. Current Medicinal Chemistry, 2012, 19(23).
| Supplier: | TargetMol |
| Supplier-Nr: | T7042 |
Properties
| Application: | PARP-1 inhibitor |
| MW: | 161.16 D |
| Formula: | C9H7NO2 |
Database Information
| CAS : | 5154-02-9| Matching products |
| KEGG ID : | K10798 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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