Tosufloxacin (tosylate)

Tosufloxacin is a fluoroquinolone antibiotic. It has activity against diverse aerobic and anaerobic bacteria in vitro. Tosufloxacin is also effective against bacterial persisters, showing significant activity against S. aureus and uropathogenic E. coli persisters. As with many other quinolones, tosufloxacin use can be associated with significant side effects.Formal Name: 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid 4-methylbenzenesulfonate. CAS Number: 115964-29-9. Molecular Formula: C19H15F3N4O3 . C7H8O3S. Formula Weight: 576.5. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml, Ethanol: slightly soluble. lambdamax: 221, 269, 341 nm. SMILES: O=C1C2=C(N=C(N3CCC(N)C3)C(F)=C2)N(C4=CC=C(F)C=C4F)C=C1C(O)=O.CC5=CC=C(S(O)(=O)=O)C=C5. InChi Code: InChI=1S/C19H15F3N4O3.C7H8O3S/c20-9-1-2-15(13(21)5-9)26-8-12(19(28)29)16(27)11-6-14(22)18(24-17(11)26)25-4-3-10(23)7-25,1-6-2-4-7(5-3-6)11(8,9)10/h1-2,5-6,8,10H,3-4,7,23H2,(H,28,29),2-5H,1H3,(H,8,9,10). InChi Key: CSSQVOKOWWIUCX-UHFFFAOYSA-N.