Thiamphenicol

Thiamphenicol is an antibiotic derived from chloramphenicol that displays a similar spectrum of activity with enhanced potency. It displays good in vitro activity against a range of multidrug resistant pathogens, including penicillin-resistant strains and methicillin-resistant S. aureus.Formal Name: 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-acetamide. CAS Number: 15318-45-3. Synonyms: NSC 522822, (+)-Thiamphenicol, Thiophenicol, WIN 5,603-2. Molecular Formula: C12H15Cl2NO5S. Formula Weight: 356.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml, Ethanol: 200 µg/ml. lambdamax: 225, 266 nm. SMILES: CS(C1=CC=C([C@@H](O)[C@H](NC(C(Cl)Cl)=O)CO)C=C1)(=O)=O. InChi Code: InChI=1S/C12H15Cl2NO5S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-16)15-12(18)11(13)14/h2-5,9-11,16-17H,6H2,1H3,(H,15,18)/t9-,10-/m1/s1. InChi Key: OTVAEFIXJLOWRX-NXEZZACHSA-N.