PC-766B

PC-766B
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay20587-1 1 mg -

6 - 10 business days*

313.00€
Cay20587-5 5 mg -

6 - 10 business days*

1,251.00€
 
PC-766B is a macrolide antibiotic produced by N. brasiliensis that is active against... more
Product information "PC-766B"
PC-766B is a macrolide antibiotic produced by N. brasiliensis that is active against Gram-positive bacteria and some fungi, yet inactive against Gram-negative bacteria. It also demonstrates antitumor activity against mouse P388 leukemia and B16 melanoma cells in vitro (IC50s = 0.1 and 0.4 ng/ml, respectively) and in vivo, but weakly inhibits the Na+,K+-ATPase compared to structurally related antibiotics.Formal Name: 16-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[(2,6-dideoxy-beta-D-arabino-hexopyranosyl)oxy]tetrahydro-2-hydroxy-5-methyl-6-[(1E,3E)-1,3-pentadien-1-yl]-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-(3Z,5E,7R,8S,9S,11E,13E,15S,16R)-oxacyclohexadeca-3,5,11,13-tetraen-2-one. CAS Number: 108375-77-5. Synonyms: Antibiotic PC-766B. Molecular Formula: C43H68O12. Formula Weight: 777.0. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: Soluble, DMSO: Soluble, Ethanol: Soluble, Methanol: Soluble. SMILES: O=C1O[C@H]([C@@H](C)[C@@H](O)[C@@H]([C@@]2(O)C[C@@H](O[C@H]3C[C@H]([C@@H]([C@@H](C)O3)O)O)[C@H](C)[C@@H](/C=C/C=C/C)O2)C)[C@@H](OC)/C=C/C=C(C)/C[C@H](C)[C@H](O)[C@H](C)/C=C(C)/C=C1\OC. InChi Code: InChI=1S/C43H68O12/c1-12-13-14-17-33-28(6)36(53-37-22-32(44)40(47)31(9)52-37)23-43(49,55-33)30(8)39(46)29(7)41-34(50-10)18-15-16-24(2)19-26(4)38(45)27(5)20-25(3)21-35(51-11)42(48)54-41/h12-18,20-21,26-34,36-41,44-47,49H,19,22-23H2,1-11H3/b13-12+,17-1. InChi Key: GBRLJEHLCUILHG-OIZCXYEVSA-N. Origin: Bacterium/Nocardia brasiliensis.
Keywords: Antibiotic PC-766B, 16-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[(2,6-dideoxy-beta-D-arabino-hexopyranosyl)oxy]tetrahydro-2-hydroxy-5-methyl-6-[(1E,3E)-1,3-pentadien-1-yl]-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-(3Z,5E,
Supplier: Cayman Chemical
Supplier-Nr: 20587

Properties

Application: Macrolide antibiotic
MW: 777 D
Formula: C43H68O12
Purity: >95%
Format: Solid

Database Information

CAS : 108375-77-5| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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