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Ertapenem is a long-acting, broad-spectrum antibiotic that is in the beta-lactam subclass known as carbapenems. It inhibits the synthesis of bacterial cell walls by attaching to penicillin-binding proteins. Ertapenem is effective against Gram-positive and Gram-negative bacteria. Resistance to ertapenem results from the expression of certain beta-lactamases and carbapenemases.Formal Name: (4R,5S,6S)-3-[[(3S,5S)-5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, disodium salt. CAS Number: 153832-38-3. Synonyms: L-749. Molecular Formula: C22H23N3O7S . 2Na. Formula Weight: 519.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 10 mg/ml. lambdamax: 295 nm. SMILES: O=C1[C@@]([C@@H](C)O)([H])[C@]2([H])N1C(C([O-])=O)=C(S[C@@H]3CN[C@H](C(NC4=CC(C([O-])=O)=CC=C4)=O)C3)[C@@H]2C.[Na+].[Na+]. InChi Code: InChI=1S/C22H25N3O7S.2Na/c1-9-16-15(10(2)26)20(28)25(16)17(22(31)32)18(9)33-13-7-14(23-8-13)19(27)24-12-5-3-4-11(6-12)21(29)30,,/h3-6,9-10,13-16,23,26H,7-8H2,1-2H3,(H,24,27)(H,29,30)(H,31,32),,/q,2*+1/p-2/t9-,10-,13+,14+,15-,16-,,/m1../s1. InChi Key: KMVRATCHVMUJHM-SHZCTIMHSA-L.
Keywords:
L-749, (4R,5S,6S)-3-[[(3S,5S)-5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, disodium salt
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