Bacitracin A (technical grade)

Bacitracin A is a polypeptide antibiotic that has been found in B. licheniformis and the main active component of the bacitracin family of polypeptide antibiotics. It is active against M. lysodeikticus when used at a concentration of 0.1 µM and forms a complex with divalent cations and the cell membrane component C55-isoprenyl pyrophosphate.Formal Name: N-[[(4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-4-thiazolyl]carbonyl]-L-leucyl-D-alpha-glutamyl-L-isoleucyl-L-lysyl-D-ornithyl-L-isoleucyl-D-phenylalanyl-L-histidyl-D-alpha-aspartyl-L-asparagine, (10->4)-lactam. CAS Number: 22601-59-8. Synonyms: NSC 45737. Molecular Formula: C66H103N17O16S. Formula Weight: 1422.7. Purity: >60%. Formulation: (Request formulation change), A solid. Solubility: DMSO: slightly soluble, Methanol: slightly, sonicated. SMILES: O=C(N[C@@H](C(N[C@@](C(N[C@@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(NCCCC1)=O)CC(N)=O)=O)CC(O)=O)=O)CC2=CN=CN2)=O)CC3=CC=CC=C3)=O)([H])[C@@H](C)CC)=O)CCCN)[C@H]1NC([C@H]([C@@H](C)CC)NC([C@@H](CCC(O)=O)NC([C@H](CC(C)C)NC([C@@H]4CSC([C@@H](N)[C@H](CC)C)=N4)=O)=O)=O)=O. InChi Code: InChI=1S/C66H103N17O16S/c1-9-35(6)52(69)66-81-48(32-100-66)63(97)76-43(26-34(4)5)59(93)74-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)75-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-72-39)77-60(94)44(27-38-18-13-12-14-19-38)80-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)73-56(40)90/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,72)(H,71,89)(H,73,90)(H,74,93)(H,75,98)(H,76,97)(H,77,94)(H,78,96)(H,79,95)(H,80,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88)/t35-,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48-,52-,53-,54-/m0/s1. InChi Key: CLKOFPXJLQSYAH-ABRJDSQDSA-N. Origin: Bacterium/Bacillus licheniformis.