Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
BPS-78601 | 50 µl | - | - |
3 - 15 business days* |
1,887.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The anti-CD19 CAR lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped... more
Product information "Anti-CD19 CAR Lentivirus (CD19 ScFv-CD8-4-1BB-CD3zeta, SIN Vector)"
The anti-CD19 CAR lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to infect almost all types of mammalian cells, including primary and non-dividing cells. These viruses transduce the ScFv portion of anti-CD19 (clone FMC63) linked to 2nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, 4-1BB and CD3zeta signaling domains (Figure 1). Note: This product transduces the same construct as the anti-CD19 CAR Lentivirus (CD19 ScFv-CD8-4-1BB-CD3zeta) (BPS Bioscience #78600), but differs in key aspects: 78601, described here, is constructed with a SIN lentivector while 78600 is not. 78601, described here, does not contain an antibiotic for selection while 78600 contains a puromycin selection so the transduced cells can be selected with puromycin. BPS Bioscience CAT # Self-Inactivation (SIN) Antibiotic selection 78601 yes no 78600 no puromycin Figure 1A. Schematic of the lenti-vector used to generate the anti-CD19 CAR lentivirus. The vector is a SIN vector, and it does not contain a mammalian selection antibiotic. Figure 1B. Construct diagram showing components of the anti-CD19 CAR.
Keywords: | CD19, B-lymphocyte antigen CD19, Differentiation antigen CD19, T-cell surface antigen Leu-12, B-lymphocyte surface antigen B4, |
Supplier: | BPS Bioscience |
Supplier-Nr: | 78601 |
Properties
Application: | Anti-CD19 CAR evaluation positive control, transduction optimization, anti-CD19 CAR-T cell generation |
Species reactivity: | human |
Database Information
KEGG ID : | K06465 | Matching products |
UniProt ID : | P15391 | Matching products |
Gene ID | GeneID 930 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -80°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
Viewed