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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
BPS-78775 | 50 µl | - | - |
3 - 15 business days* |
2,098.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The anti-CD19 CAR lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped... more
Product information "Anti-CD19 CAR Lentivirus (CD19 ScFv-CD8-4-1BB-CD3zeta, eGFP)"
The anti-CD19 CAR lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to ready to transduce most mammalian cells, including primary and non-dividing cells. These viruses transduce the ScFv portion of anti-CD19 (clone FMC63) linked to 2nd generation CAR (Chimeric Antigen Receptor), containing CD8 hinge and transmembrane domains, 4-1BB and CD3zeta signaling domains. This construct also includes an IRES- enhanced green fluorescent protein (eGFP) sequence downstream of anti-CD19 CAR cassette to facilitate analysis and sorting of transduced cells (Figure 1). Figure 1. (A) Schematic of the lenti-vector used to generate the anti-CD19 CAR lentivirus. The vector is a SIN vector, and it contains eGFP. (B) Construct diagram showing components of the anti-CD19 CAR. Note: This product transduces the same anti-CD19 CAR construct (CD19 ScFv-CD8-4-1BB-CD3zeta) as other available anti-CD19 CAR Lentiviruses (BPS Bioscience #78600, 78601 and 78602), but differ in key aspects. This product contains an eGFP reporter/selection marker so the transduced cells can be sorted based on eGFP expression. Please see table below. BPS Bioscience Catalog # Self-Inactivation (SIN) Selection Marker 78600 no puromycin 78601 yes no 78602 yes puromycin 78775 yes eGFP
Keywords: | CD19, B-lymphocyte antigen CD19, Differentiation antigen CD19, T-cell surface antigen Leu-12, B-lymphocyte surface antigen B4, |
Supplier: | BPS Bioscience |
Supplier-Nr: | 78775 |
Properties
Application: | Positive control, transduction optimization, anti-CD19 CAR-T cell generation (RUO) |
Species reactivity: | human |
Database Information
KEGG ID : | K06465 | Matching products |
UniProt ID : | P15391 | Matching products |
Gene ID : | GeneID 930 | Matching products |
Handling & Safety
Storage: | -80°C (avoid repeat freezing and thawing cycles) |
Shipping: | -80°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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