TCR Knockout NFAT-Luciferase Reporter Jurkat Cell Line

TCR Knockout NFAT-Luciferase Reporter Jurkat Cell Line

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
BPS-78556	2 vials		-	-	3 - 15 business days*		14,586.00€

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This cell line is a knockout of TCR (T Cell Receptor). The TRAC (T-Cell Receptor Alpha Constant)... more

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Product information "TCR Knockout NFAT-Luciferase Reporter Jurkat Cell Line"

This cell line is a knockout of TCR (T Cell Receptor). The TRAC (T-Cell Receptor Alpha Constant) and TRBC1 (T-Cell Receptor Beta Constant 1) domains of the TCRalpha/beta chains were genetically removed by CRISPR/Cas9 genome editing from recombinant Jurkat cells stably expressing the firefly luciferase gene under the control of NFAT response elements. This cell line has been functionally validated and does not respond to anti-CD3 agonist antibodies, as opposed to parental NFAT-Luciferase Reporter Jurkat cells (BPS Bioscience #60621).

Keywords:	CRISPR, TCR knockout, CAR-T, killing assay,
Supplier:	BPS Bioscience
Supplier-Nr:	78556

Properties

Application:	CAR-T-specific cell killing determination control
Species reactivity:	human

Database Information

UniProt ID :

P01848 | Matching products

Handling & Safety

Storage:	Liquid nitrogen
Shipping:	-80°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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