IKCA1 (KCNN4) - HEK293 recombinant cell line (2 x 10(6) cells)

Recombinant HEK293 cell line expressing human IKCA1, also known as KCNN4 (Intermediate conductance calcium-activated potassium channel protein 4), IK1, hKCa4, and hSK4), Genbank Accession No. NM_002250. Each vial contains 2 X 10(6) cells in 1 ml of 10% DMSO. IKCA1 is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. Functional validation: N-terminal FLAG-tagged human IKCA1 has been stably expressed in HEK293 cell line and its expression was confirmed by western blotting.