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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
BPS-82436 | 2 vials | - | - |
3 - 15 business days* |
6,269.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
HRE Luciferase Reporter ME-180 Cell Line is designed to monitor the activity of hypoxia-inducible... more
Product information "HRE Luciferase Reporter ME-180 Cell Line"
HRE Luciferase Reporter ME-180 Cell Line is designed to monitor the activity of hypoxia-inducible factors (HIFs). It contains a firefly luciferase reporter driven by multiple copies of hypoxia response element (HRE) located upstream of the minimal TATA promoter. As oxygen becomes rate limiting, HIFs form heterodimers that recognize cognate HREs, inducing transcription of the luciferase reporter. The cell line has been functionally validated in response to the hypoxia-mimetics cobalt chloride (CoCl2) and Deferoxamine (DFO). Interested in screening and profiling inhibitors, blocking antibodies, or activators without the need to purchase and license the cell line? Check out our Cell Signaling Pathway Screening.
Keywords: | bHLHe78, BHLHE78, HIF1-alpha, HIF-1-alpha, Member of PAS protein 1, ARNT-interacting protein, PAS domain-containing protein 8, Hypoxia-inducible factor 1-alpha, Basic-helix-loop-helix-PAS protein MOP1, Class E basic helix-loop-helix protein 78, |
Supplier: | BPS Bioscience |
Supplier-Nr: | 82436 |
Properties
Application: | Hypoxia-related signaling pathway studies |
Species reactivity: | human |
Database Information
KEGG ID : | K08268 | Matching products |
UniProt ID : | Q16665 | Matching products |
Gene ID : | GeneID 3091 | Matching products |
Handling & Safety
Storage: | Liquid nitrogen |
Shipping: | -80°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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