HRE Luciferase Reporter ME-180 Cell Line

Item number Size Datasheet Manual SDS Delivery time Quantity Price
BPS-82436 2 vials - -

3 - 15 business days*

6,269.00€
 
HRE Luciferase Reporter ME-180 Cell Line is designed to monitor the activity of hypoxia-inducible... more
Product information "HRE Luciferase Reporter ME-180 Cell Line"
HRE Luciferase Reporter ME-180 Cell Line is designed to monitor the activity of hypoxia-inducible factors (HIFs). It contains a firefly luciferase reporter driven by multiple copies of hypoxia response element (HRE) located upstream of the minimal TATA promoter. As oxygen becomes rate limiting, HIFs form heterodimers that recognize cognate HREs, inducing transcription of the luciferase reporter. The cell line has been functionally validated in response to the hypoxia-mimetics cobalt chloride (CoCl2) and Deferoxamine (DFO). Interested in screening and profiling inhibitors, blocking antibodies, or activators without the need to purchase and license the cell line? Check out our Cell Signaling Pathway Screening.
Keywords: bHLHe78, BHLHE78, HIF1-alpha, HIF-1-alpha, Member of PAS protein 1, ARNT-interacting protein, PAS domain-containing protein 8, Hypoxia-inducible factor 1-alpha, Basic-helix-loop-helix-PAS protein MOP1, Class E basic helix-loop-helix protein 78,
Supplier: BPS Bioscience
Supplier-Nr: 82436

Properties

Application: Hypoxia-related signaling pathway studies
Species reactivity: human

Handling & Safety

Storage: Liquid nitrogen
Shipping: -80°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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