Rat vascular cell adhesion protein 1 (VCAM-1/CD106) ELISA kit

Sample Types: serum, plasma, tissue homogenates Detection Range: 15.6 ng/mL-1000 ng/mL Sensitivity: 3.9 ng/mL Assay Principle: quantitative Measurement: SandwichAssay Time: 1-5h Sample Volume: 50-100ulDetection Wavelength: 450 nmProtein function: Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha- 4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. [The UniProt Consortium]