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![Rat HIF-1alpha (Hypoxia Inducible Factor 1 Alpha) ELISA Kit](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-EL-R0513.24 | 24 tests | - |
7 - 16 business days* |
118.00€
|
|||
E-EL-R0513.48 | 48 tests | - |
7 - 16 business days* |
384.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of HIF-1alpha in... more
Product information "Rat HIF-1alpha (Hypoxia Inducible Factor 1 Alpha) ELISA Kit"
The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of HIF-1alpha in serum, plasma and other biological fluids. Detection Range: 7.81--500pg/mL. Sensitivity: 4.69pg/mL. Protein function: Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Activation requires recruitment of transcriptional coactivators such as CREBBP and EP300. Activity is enhanced by interaction with both, NCOA1 or NCOA2. Interaction with redox regulatory protein APEX seems to activate CTAD and potentiates activation by NCOA1 and CREBBP. Involved in the axonal distribution and transport of mitochondria in neurons during hypoxia. [The UniProt Consortium]
Keywords: | Hif1a, HIF1-alpha, HIF-1-alpha, Hypoxia-inducible factor 1-alpha |
Supplier: | Elabscience |
Supplier-Nr: | E-EL-R0513 |
Properties
Application: | ELISA |
Species reactivity: | rat |
Format: | Solid Phase |
Database Information
KEGG ID : | K08268 | Matching products |
UniProt ID : | O35800 | Matching products |
Gene ID | GeneID 29560 | Matching products |
Handling & Safety
Storage: | vT |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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