Rat EAAT3 (Excitatory Amino Acid Transporter 3)ELISA Kit (RTFI01428)

Rat EAAT3 (Excitatory Amino Acid Transporter 3)ELISA Kit from Assay Genie is a pre-coated immunoassay with a high sensitivity and broad range and has been designed to measure Rat EAAT3 (Excitatory Amino Acid Transporter 3)ELISA Kit in serum, plasma & cell culture supernatant samples. The Rat EAAT3 (Excitatory Amino Acid Transporter 3)ELISA Kit accurately measures natural Rat EAAT3 (Excitatory Amino Acid Transporter 3)ELISA Kit levels quantified versus standard curves obtained and is based on antibodies raised against a recombinant Rat EAAT3 (Excitatory Amino Acid Transporter 3)ELISA Kit peptide. Protein function: Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:9011753, PubMed:11242046). Can also transport L-cysteine. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport, this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate. Contributes to glutathione biosynthesis and protection against oxidative stress via its role in L-glutamate and L-cysteine transport. Negatively regulated by ARL6IP5 (PubMed:11242046). [The UniProt Consortium]