Rabbit TNF-alpha (Tumor Necrosis Factor Alpha) ELISA Kit

Rabbit TNF-alpha (Tumor Necrosis Factor Alpha) ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-AEES00563.96 96 assays - -

9 - 20 business days*

534.00€
 
ELISA Type: Sandwich. Detection Range: 15.63-1000µg/mL. Sensitivity: 9.38µg/mL. Sample Types:... more
Product information "Rabbit TNF-alpha (Tumor Necrosis Factor Alpha) ELISA Kit"
ELISA Type: Sandwich. Detection Range: 15.63-1000µg/mL. Sensitivity: 9.38µg/mL. Sample Types: Serum, plasma and other biological fluids. Protein function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance. Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6. Promotes osteoclastogenesis and therefore mediates bone resorption. [The UniProt Consortium]
Keywords: TNF, TNFA
Supplier: Assay Genie
Supplier-Nr: AEES00563

Properties

Application: Sandwich
Species reactivity: rabbit
Format: Solid Phase

Handling & Safety

Storage: vT
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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