PAK3 (Phospho-Ser154) Colorimetric Cell-Based ELISA Kit

Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CBCAB01653.96 96 assays (2 x 96-well microplates) - -

9 - 20 business days*

641.00€
 
PAK3 (Phospho-Ser154) Colorimetric Cell-Based ELISA Kit Protein function: Serine/threonine... more
Product information "PAK3 (Phospho-Ser154) Colorimetric Cell-Based ELISA Kit"
PAK3 (Phospho-Ser154) Colorimetric Cell-Based ELISA Kit Protein function: Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration. Additionally, phosphorylates TNNI3/troponin I to modulate calcium sensitivity and relaxation kinetics of thin myofilaments. May also be involved in early neuronal development. [The UniProt Consortium]
Keywords: PAK3, OPHN3, PAK-3, Beta-PAK, EC=2.7.11.1, Oligophrenin-3, p21-activated kinase 3, Serine/threonine-protein kinase PAK 3
Supplier: Assay Genie
Supplier-Nr: CBCAB01653

Properties

Application: In-cell ELISA

Database Information

KEGG ID : K05733 | Matching products
UniProt ID : O75914 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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