MS Mouse IL-1beta (Interleukin 1 Beta) ELISA Kit

This ELISA kit applies to the in vitro quantitative determination of Mouse IL-1beta concentrations in serum, plasma and other biological fluids. Photometric. Detection Range: 7.81~500pg/mL. Sensitivity: 3.55pg/mL. Protein function: Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. [The UniProt Consortium] Assay Time: 3.5h. Tested Sample Types: Serum, plasma and other biological fluids