Mouse TNFSF18 - GITRL ELISA Kit

Mouse TNFSF18 - GITRL ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
KOA0782 1 kit - -

6 - 10 business days*

848.00€
 
Natural and recombinant mouse TNFSF18. There is no detectable cross-reactivity with other... more
Product information "Mouse TNFSF18 - GITRL ELISA Kit"
Natural and recombinant mouse TNFSF18. There is no detectable cross-reactivity with other relevant proteins. Protein function: Cytokine that binds to TNFRSF18/AITR/GITR (PubMed:14521928, PubMed:14647196). Regulates T-cell responses (PubMed:14647196). Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation (PubMed:14608036, PubMed:15128759). Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B (PubMed:14521928, PubMed:14647196, PubMed:18178614). Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1. Promotes leukocyte adhesion to endothelial cells (PubMed:23892569). Regulates migration of monocytes from the splenic reservoir to sites of inflammation (PubMed:24107315). [The UniProt Consortium]
Keywords: Gitrl, GITRL, Tnfsf18, GITR ligand, Glucocorticoid-induced TNF-related ligand, Tumor necrosis factor ligand superfamily member 18
Supplier: Rockland Immunochemicals
Supplier-Nr: KOA0782

Properties

Application: ELISA
Host: Mouse
Species reactivity: mouse
Immunogen: Expression system for standard: NSO, Immunogen sequence: T47-S173
Format: Solid Phase

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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