Mouse SHH (Hedgehog Homolog, Sonic) ELISA Kit

The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of SHH in serum, plasma and other biological fluids. Detection Range: 15.63--1000pg/mL. Sensitivity: 9.38pg/mL. Protein function: Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (PubMed:8824192, PubMed:7891723). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (PubMed:8824192). Both activities occur in the reticulum endoplasmic (PubMed:21357747). Once cleaved, ShhC is degraded in the endoplasmic reticulum (PubMed:21357747). [The UniProt Consortium]