Mouse CD47 (Leukocyte surface antigen CD47) ELISA Kit

Mouse CD47 (Leukocyte surface antigen CD47) ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-AEFI00524.96 96 assays - -

9 - 20 business days*

641.00€
 
ELISA Type: Sandwich ELISA, Double Antibody. Detection Range: 0.156-10µg/mL. Sensitivity:... more
Product information "Mouse CD47 (Leukocyte surface antigen CD47) ELISA Kit"
ELISA Type: Sandwich ELISA, Double Antibody. Detection Range: 0.156-10µg/mL. Sensitivity: 0.094µg/mL. Sample Types: Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples. Protein function: Adhesive protein that mediates cell-to-cell interactions. Acts as a receptor for thrombospondin THBS1 and as modulator of integrin signaling through the activation of heterotrimeric G proteins. Involved in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, and immunoregulation (PubMed:20610415, PubMed:23591719, PubMed:27742621). Plays a role in modulating pulmonary endothelin EDN1 signaling (PubMed:27742621). Modulates nitrous oxide (NO) signaling, in response to THBS1, hence playing a role as a pressor agent, supporting blood pressure (PubMed:20610415). Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. Positively modulates FAS-dependent apoptosis in T-cells, perhaps by enhancing FAS clustering (PubMed:15917238). Plays a role in suppressing angiogenesis and may be involved in metabolic dysregulation during normal aging (PubMed:32679764). In response to THBS1, negatively modulates wound healing (PubMed:18156939). Inhibits stem cell self-renewal, in response to THBS1, probably by regulation of the stem cell transcription factors POU5F1/OCT4, SOX2, MYC/c-Myc and KLF4 (PubMed:23591719). May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells (PubMed:10856220). [The UniProt Consortium]
Keywords: IAP, Cd47, CD47, Integrin-associated protein, Leukocyte surface antigen CD47
Supplier: Assay Genie
Supplier-Nr: AEFI00524

Properties

Application: Sandwich ELISA, Double Antibody
Species reactivity: mouse
Format: Solid Phase

Handling & Safety

Storage: vT
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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