Human Membrane-associated progesterone receptor component 1 (PGRMC1) ELISA kit

Sample Types: serum, plasma, tissue homogenates, cell lysates Detection Range: 47 pg/mL-3000 pg/mL Sensitivity: 11.7 pg/mL Assay Principle: quantitative Measurement: SandwichAssay Time: 1-5h Sample Volume: 50-100ulDetection Wavelength: 450 nmProtein function: Component of a progesterone-binding protein complex (PubMed:28396637). Binds progesterone (PubMed:25675345). Has many reported cellular functions (heme homeostasis, interaction with CYPs). Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan. Intracellular heme chaperone. Regulates heme synthesis via interactions with FECH and acts as a heme donor for at least some hemoproteins (PubMed:27599036). [The UniProt Consortium]