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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| KOA0503 | 1 kit | - | - |
6 - 10 business days* |
848.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Natural and recombinant human Diablo. There is no detectable cross-reactivity with other relevant... more
Product information "Human Diablo - SMAC ELISA Kit"
Natural and recombinant human Diablo. There is no detectable cross-reactivity with other relevant proteins. Protein function: Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases. Isoform 3 attenuates the stability and apoptosis- inhibiting activity of XIAP/BIRC4 by promoting XIAP/BIRC4 ubiquitination and degradation through the ubiquitin-proteasome pathway. Isoform 3 also disrupts XIAP/BIRC4 interacting with processed caspase-9 and promotes caspase-3 activation. Isoform 1 is defective in the capacity to down-regulate the XIAP/BIRC4 abundance. [The UniProt Consortium]
| Keywords: | SMAC, Smac, DIABLO, Diablo homolog, mitochondrial, Direct IAP-binding protein with low pI, Second mitochondria-derived activator of caspase |
| Supplier: | Rockland Immunochemicals |
| Supplier-Nr: | KOA0503 |
Properties
| Application: | ELISA |
| Host: | Human |
| Species reactivity: | human |
| Immunogen: | Expression system for standard: E.coli, Immunogen sequence: A56-D239 |
| Format: | Solid Phase |
Database Information
| KEGG ID : | K10522 | Matching products |
| UniProt ID : | Q9NR28 | Matching products |
| Gene ID | GeneID 56616 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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