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Product information "Cysteinyl Leukotriene ELISA Kit"
Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid via the 5-lipoxygenase (5-LO) pathway in leukocytes. LTC4, LTD4, and LTE4 are collectively referred to as cysteinyl leukotrienes (CysLTs). LTC4 and LTD4 are potent mediators of asthma and hypersensitivity. They induce bronchoconstriction, increase microvascular permeability, and are vasoconstrictors of coronary arteries. The biological activity of LTE4 is much lower in most systems studied, but its presence reflects the prior existence of LTC4 and LTD4. Cayman's CysLT ELISA Kit is a competitive assay based on a proprietary high-affinity monoclonal antibody that can be used for quantification of CysLT in urine and other sample matrices. The assay has a range from 8.6-2,500 pg/ml and a sensitivity (80% B/B0) of approximately 40.5 pg/ml.Synonyms: CysLT EIA Kit. Assay Range: 8.6-2,500 pg/ml. Sensitivity: 80% B/B0: 40.5 pg/ml. Mid-point: 50% B/B0: 100-160 pg/ml. Cross Reactivity: (Leukotriene C4) 100%, (Leukotriene D4) 100%, (Leukotriene E4) 79%, (5,6-DiHETE) 3.7%, (Leukotriene B4) 1.3%, (5(S)-HETE) 0.04%, (Arachidonic Acid) <0.01%. Origin: Animal/Eel, Animal/Bovine, Animal/Mouse.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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