Citrullinated Histone H3 (Clone 11D3) ELISA Kit

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
Cay501620-96	96 wells		-		6 - 10 business days*		769.00€

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Histone H3 is citrullinated by peptidylarginine deiminase 4 (PAD4) at residues R2, R8, and R17... more

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Product information "Citrullinated Histone H3 (Clone 11D3) ELISA Kit"

Histone H3 is citrullinated by peptidylarginine deiminase 4 (PAD4) at residues R2, R8, and R17 during the processes of epigenetic chromatin remodeling and neutrophil extracellular trap (NET) formation. In vitro, citrullinated H3 (CitH3) is released from neutrophils that have been stimulated with calcium ionophore during the process of NETosis, and can be freed from NETs by treatment with nuclease. The measurement of CitH3, either in cell lysates or released during NETosis can be used as a functional readout of pharmacological PAD inhibition.Synonyms: CitH3 (Clone 11D3) EIA Kit. Clone Designation: 11D3. Limit of Detection: 0.1 ng/ml. Assay Range: 0.15-10 ng/ml. Lower Limit of Quantification: 0.3 ng/ml. Origin: Animal/Mouse, Animal/Bovine.

Keywords:	CitH3 (Clone 11D3) EIA Kit
Supplier:	Cayman Chemical
Supplier-Nr:	501620

Properties

Application:	ELISA
Clone:	11D3
Format:	Solid Phase

Database Information

KEGG ID :	K11253 \| Matching products
UniProt ID :	P68431 \| Matching products
Gene ID :	GeneID 8350 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	-20°C (International: -20°C)
Signal Word:	Danger
GHS Hazard Pictograms:
H Phrases:	H302, H314, H315, H318, H319, H335, H360, H373
P Phrases:	P201, P202, P260, P261, P264, P270, P271, P280, P312, P314, P321, P363, P301+P310, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501