CD163, Mouse, BioAssay(TM) DuoSet ELISA Development Kit (CD163, GHI/61, HbSR, M130, RM3/1, Hemoglobi

CD163, also known as hemoglobin scavenger receptor, is a type I transmembrane protein expressed exclusively in monocytes and macrophages. It is a scavenger receptor cysteine-rich superfamily (SRCR-SF) protein that contains nine SRCR motifs in its extracellular region. Two alternatively spliced cytoplasmic variants of human CD163 exist. A soluble form of CD163 can also be released by metalloproteinase-mediated shedding of the extracellular domain. CD163 mediates the endocytosis of haptoglobin-hemoglobin complexes. Sample Type: Cell culture supernates, Intended Use: This BioAssay(TM) DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant mouse CD163. DuoSets are designed for the analysis of cell culture supernates. Range: ~0.312-20pg/ml, Specificity: Recognizes natural and recombinant mouse CD163. Kit Components: Rat anti-mouse CD163 capture antibody, 1x vial, Biotinylated rat anti-mouse CD163 detection antibody, 1x vial, Recombinant mouse CD163 standard, 3x vials, Streptavidin-HRP, 1x vial, Storage and Stability: Store other components at 4°C. Stable for at least 6 months For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.