PXR (Rat) Reporter Assay System

PXR (Rat) Reporter Assay System
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IB-R07001 96 wells (1 x 96 -well format assays) -

7 - 11 business days*

1,448.00€
IB-R07001-32 96 wells (3 x 32 assays in 96 -well format) -

7 - 11 business days*

1,536.00€
 
Protein function: Nuclear receptor that binds and is activated by a variety of endogenous and... more
Product information "PXR (Rat) Reporter Assay System"
Protein function: Nuclear receptor that binds and is activated by a variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, endogenous compounds and drugs. Response to specific ligands is species-specific, due to differences in the ligand- binding domain. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes. [The UniProt Consortium]
Keywords: Pxr, Nr1i2, Pregnane X receptor, Orphan nuclear receptor PXR, Nuclear receptor subfamily 1 group I member 2
Supplier: Indigo Biosciences
Supplier-Nr: R07001

Properties

Application: Functional activity screening
Species reactivity: rat
Format: Solid Phase

Handling & Safety

Storage: -80°C
Shipping: -80°C (International: -80°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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