PXR (human) Reporter Assay Kit

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
IB-IB07001	96 wells		-		7 - 11 business days*		1,448.00€
IB-IB07001-32	96 wells (3 x 32 wells)		-		7 - 11 business days*		1,536.00€

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Protein function: Nuclear receptor that binds and is activated by variety of endogenous and... more

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Product information "PXR (human) Reporter Assay Kit"

Protein function: Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the antibiotic rifampicin and various plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Response to specific ligands is species-specific. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes. [The UniProt Consortium]

Keywords:	SXR, PXR, NR1I2, Pregnane X receptor, Orphan nuclear receptor PXR, Orphan nuclear receptor PAR1, Steroid and xenobiotic receptor, Nuclear receptor subfamily 1 group I member 2
Supplier:	Indigo Biosciences
Supplier-Nr:	IB07001