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Product information "Annexin V-FITC/PI Apoptosis Kit"
Annexin V is a member of the annexin family, which binds to phosphatidylserine (PS) in a calcium-dependent manner. The Annexin V-labeled fluorescein bind specifically to the PS on the outer leaflet apoptotic cell membrane and can be detected with flow cytometry or fluorescence microscope. Nuclear dyes (PI, DAPI, 7-AAD) have a high DNA binding constant and is efficiently excluded by intact cells. It is useful for DNA analysis and dead cell discrimination during flow cytometric analysis. Due to late apoptosis or loss of membrane integrity in necrotic cells, nuclear dyes can enter cells to stain DNA, and when used in combination with Annexin V, cells in different apoptotic stages can be distinguished. Protein function: This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. [The UniProt Consortium]
Keywords:
PP4, ANX5, ANXA5, PAP-I, CPB-I, Annexin V, Annexin-5, VAC-alpha, Annexin A5, Anchorin CII, Endonexin II, Lipocortin V, Calphobindin I, Thromboplastin inhibitor, Vascular anticoagulant-alpha, Placental anticoagulant protein 4, Annexin V-FITC/PI Apoptosis D
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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