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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay702490-384 | 384 wells | - | - |
6 - 10 business days* |
669.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Cayman's sPLA2 (Type V) Inhibitor Screening Assay Kit provides a robust and easy-to-use platform... more
Product information "sPLA2 (Type V) Inhibitor Screening Assay Kit"
Cayman's sPLA2 (Type V) Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human sPLA2 type V. The assay uses diheptanoyl thio-PG, a sulfur-containing analog of phosphatidylglycerol, which is the preferred substrate of sPLA2 type V. Upon hydrolysis by sPLA2 type V at the sn-2 position, the free thiol can be detected by the sPLA2 Assay Probe. This results in a product that can be easily quantified by measuring absorbance at a wavelength of 410 nm. A potent and reversible inhibitor, LY315920 (included in this kit as sPLA2 Control Inhibitor), inhibits the enzyme with an IC50 value of approximately 100 nM. As an alternative, Cayman offers sPLA2 (Type V) Inhibitor Screening Kit (PC Substrate) (Cay-10004883), which uses a PC-based substrate.Synonyms: GVsPLA2, Phosphatidylcholine 2-acylhydrolase 5, Phospholipase A2 Group V, PLA2G5, Secretory Phospholipase A2 (Type V), sPLA2-V.
Keywords: | GVsPLA2, Phosphatidylcholine 2-acylhydrolase 5, Phospholipase A2 Group V, PLA2G5, Secretory Phospholipase A2 (Type V), sPLA2-V |
Supplier: | Cayman Chemical |
Supplier-Nr: | 702490 |
Properties
Application: | Inhibitor screening |
Species reactivity: | human |
Database Information
KEGG ID : | K01047 | Matching products |
UniProt ID : | P39877 | Matching products |
Gene ID | GeneID 5322 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -80°C (International: -80°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
|
H Phrases: | H225, H227, H301, H311, H315, H319, H331, H336, H351, H361, H370, H372 |
P Phrases: | P201, P202, P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P280, P301+310, P302+352, P303+361+353, P304+340, P305+351+338, P308+311, P308+313, P311, P312, P314, P321, P330, P332+313, P337+313, P361+364, P362+364, P370+378, P403, P403+233, P403+235, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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