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![GPX4 Inhibitor Screening Assay Kit](https://www.biomol.com/media/image/9e/05/01/Cay701880-96_600x600.png)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay701880-96 | 96 wells | - |
6 - 10 business days* |
700.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Cayman's GPX4 Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for... more
Product information "GPX4 Inhibitor Screening Assay Kit"
Cayman's GPX4 Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human GPX4, a negative regulator of the ferroptosis pathway. The assay measures GPX4 indirectly by a coupled reaction with glutathione reductase (GR). Oxidized glutathione (GSSG), produced upon reduction of hydroperoxide by GPX4, is recycled to its reduced state by GR and NADPH. The oxidation of NADPH to NADP+ is accompanied by a decrease in absorbance at 340 nm. The rate of decrease in A340 is directly proportional to GPX4 activity. The GPX4 inhibitor ML-162 is included as a positive control.Synonyms: Glutathione Peroxidase 4, PhGPx, Phospholipid Hydroperoxide Glutathione Peroxidase. Origin: Animal/Bovine.
Keywords: | GPx-4, PHGPx, GSHPx-4, EC=1.11.1.12, Glutathione peroxidase 4, Phospholipid hydroperoxide glutathione peroxidase |
Supplier: | Cayman Chemical |
Supplier-Nr: | 701880 |
Properties
Application: | Photometric inhibitor screening assay |
Database Information
KEGG ID : | K05361 | Matching products |
UniProt ID : | P36969 | Matching products |
Gene ID | GeneID 2879 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -80°C (International: -80°C) |
Signal Word: | Warning |
H Phrases: | H227 |
P Phrases: | P210, P280, P370+P378, P403, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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